Effect of alcohol measured by dynamic posturography.
Identifieur interne : 001710 ( Main/Exploration ); précédent : 001709; suivant : 001711Effect of alcohol measured by dynamic posturography.
Auteurs : T. Ledin [Suède] ; L M OdkvistSource :
- Acta oto-laryngologica. Supplementum [ 0365-5237 ] ; 1991.
Descripteurs français
- KwdFr :
- Adulte (MeSH), Analyse de variance (MeSH), Consommation d'alcool (MeSH), Humains (MeSH), Mâle (MeSH), Nystagmus physiologique (effets des médicaments et des substances chimiques), Posture (MeSH), Équilibre postural (effets des médicaments et des substances chimiques), Éthanol (pharmacologie), Éthanol (sang).
- MESH :
- effets des médicaments et des substances chimiques : Nystagmus physiologique, Équilibre postural.
- pharmacologie : Éthanol.
- sang : Éthanol.
- Adulte, Analyse de variance, Consommation d'alcool, Humains, Mâle, Posture.
English descriptors
- KwdEn :
- MESH :
- chemical , blood : Ethanol.
- chemical , pharmacology : Ethanol.
- drug effects : Nystagmus, Physiologic, Postural Balance.
- Adult, Alcohol Drinking, Analysis of Variance, Humans, Male, Posture.
Abstract
Thirteen healthy male volunteers aged 21-42 years (mean 27 years) were assessed by dynamic posturography before and after ingestion of alcohol. Each subject was given 0.6 g alcohol per kg body weight in fruit juice to be drunk within 10 min. Alcohol levels in blood samples at 15, 45 and 75 min after ingestion were assessed by gas chromatography. Posturographic measurements were conducted at 30 and 60 min after alcohol administration. Dynamic posturography comprises a sensory organization part in which the support surface and visual surround are either stable or referenced to the patient's sway and the test conditions are eyes open or eyes closed. In a movement coordination part the platform makes active movements. Alcohol levels were 0.40% (SD 0.14) after 45 min and 0.51% (SD 0.14) at 75 min. All subjects presented positional alcohol nystagmus and gaze nystagmus after 45 min. In the sensory organization part of the dynamic posturography in test conditions with eyes closed and the head in neutral position, both with stable (p less than 0.039) and sway-referenced platform (p less than 0.017), alcohol effects were found. In the test condition with sway referenced platform and stable visual surround the effect of alcohol was close to significance (p less than 0.069). When the head was tilted to either side, no effect of alcohol was detected, nor in the movement coordination test. It is concluded that dynamic posturography can detect the effect of alcohol on static and dynamic equilibrium. Test conditions with absent vision appear to be the most sensitive. The results in static conditions are well in agreement with previous studies; the findings under dynamic conditions are new.
DOI: 10.3109/00016489109131475
PubMed: 1927474
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Ledin</name><affiliation wicri:level="1"><nlm:affiliation>Department of ENT, University Hospital, Linköping, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of ENT, University Hospital, Linköping</wicri:regionArea><wicri:noRegion>Linköping</wicri:noRegion></affiliation></author><author><name sortKey="Odkvist, L M" sort="Odkvist, L M" uniqKey="Odkvist L" first="L M" last="Odkvist">L M Odkvist</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1991">1991</date><idno type="RBID">pubmed:1927474</idno><idno type="pmid">1927474</idno><idno type="doi">10.3109/00016489109131475</idno><idno type="wicri:Area/Main/Corpus">001713</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001713</idno><idno type="wicri:Area/Main/Curation">001713</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">001713</idno><idno type="wicri:Area/Main/Exploration">001713</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Effect of alcohol measured by dynamic posturography.</title><author><name sortKey="Ledin, T" sort="Ledin, T" uniqKey="Ledin T" first="T" last="Ledin">T. Ledin</name><affiliation wicri:level="1"><nlm:affiliation>Department of ENT, University Hospital, Linköping, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of ENT, University Hospital, Linköping</wicri:regionArea><wicri:noRegion>Linköping</wicri:noRegion></affiliation></author><author><name sortKey="Odkvist, L M" sort="Odkvist, L M" uniqKey="Odkvist L" first="L M" last="Odkvist">L M Odkvist</name></author></analytic><series><title level="j">Acta oto-laryngologica. Supplementum</title><idno type="ISSN">0365-5237</idno><imprint><date when="1991" type="published">1991</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Alcohol Drinking (MeSH)</term><term>Analysis of Variance (MeSH)</term><term>Ethanol (blood)</term><term>Ethanol (pharmacology)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Nystagmus, Physiologic (drug effects)</term><term>Postural Balance (drug effects)</term><term>Posture (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term><term>Analyse de variance (MeSH)</term><term>Consommation d'alcool (MeSH)</term><term>Humains (MeSH)</term><term>Mâle (MeSH)</term><term>Nystagmus physiologique (effets des médicaments et des substances chimiques)</term><term>Posture (MeSH)</term><term>Équilibre postural (effets des médicaments et des substances chimiques)</term><term>Éthanol (pharmacologie)</term><term>Éthanol (sang)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Ethanol</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Ethanol</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Nystagmus, Physiologic</term><term>Postural Balance</term></keywords><keywords scheme="MESH" qualifier="effets des médicaments et des substances chimiques" xml:lang="fr"><term>Nystagmus physiologique</term><term>Équilibre postural</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Éthanol</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Éthanol</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Alcohol Drinking</term><term>Analysis of Variance</term><term>Humans</term><term>Male</term><term>Posture</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Analyse de variance</term><term>Consommation d'alcool</term><term>Humains</term><term>Mâle</term><term>Posture</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Thirteen healthy male volunteers aged 21-42 years (mean 27 years) were assessed by dynamic posturography before and after ingestion of alcohol. Each subject was given 0.6 g alcohol per kg body weight in fruit juice to be drunk within 10 min. Alcohol levels in blood samples at 15, 45 and 75 min after ingestion were assessed by gas chromatography. Posturographic measurements were conducted at 30 and 60 min after alcohol administration. Dynamic posturography comprises a sensory organization part in which the support surface and visual surround are either stable or referenced to the patient's sway and the test conditions are eyes open or eyes closed. In a movement coordination part the platform makes active movements. Alcohol levels were 0.40% (SD 0.14) after 45 min and 0.51% (SD 0.14) at 75 min. All subjects presented positional alcohol nystagmus and gaze nystagmus after 45 min. In the sensory organization part of the dynamic posturography in test conditions with eyes closed and the head in neutral position, both with stable (p less than 0.039) and sway-referenced platform (p less than 0.017), alcohol effects were found. In the test condition with sway referenced platform and stable visual surround the effect of alcohol was close to significance (p less than 0.069). When the head was tilted to either side, no effect of alcohol was detected, nor in the movement coordination test. It is concluded that dynamic posturography can detect the effect of alcohol on static and dynamic equilibrium. Test conditions with absent vision appear to be the most sensitive. The results in static conditions are well in agreement with previous studies; the findings under dynamic conditions are new.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">1927474</PMID><DateCompleted><Year>1991</Year><Month>11</Month><Day>07</Day></DateCompleted><DateRevised><Year>2019</Year><Month>09</Month><Day>03</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0365-5237</ISSN><JournalIssue CitedMedium="Print"><Volume>481</Volume><PubDate><Year>1991</Year></PubDate></JournalIssue><Title>Acta oto-laryngologica. Supplementum</Title><ISOAbbreviation>Acta Otolaryngol Suppl</ISOAbbreviation></Journal><ArticleTitle>Effect of alcohol measured by dynamic posturography.</ArticleTitle><Pagination><MedlinePgn>576-81</MedlinePgn></Pagination><Abstract><AbstractText>Thirteen healthy male volunteers aged 21-42 years (mean 27 years) were assessed by dynamic posturography before and after ingestion of alcohol. Each subject was given 0.6 g alcohol per kg body weight in fruit juice to be drunk within 10 min. Alcohol levels in blood samples at 15, 45 and 75 min after ingestion were assessed by gas chromatography. Posturographic measurements were conducted at 30 and 60 min after alcohol administration. Dynamic posturography comprises a sensory organization part in which the support surface and visual surround are either stable or referenced to the patient's sway and the test conditions are eyes open or eyes closed. In a movement coordination part the platform makes active movements. Alcohol levels were 0.40% (SD 0.14) after 45 min and 0.51% (SD 0.14) at 75 min. All subjects presented positional alcohol nystagmus and gaze nystagmus after 45 min. In the sensory organization part of the dynamic posturography in test conditions with eyes closed and the head in neutral position, both with stable (p less than 0.039) and sway-referenced platform (p less than 0.017), alcohol effects were found. In the test condition with sway referenced platform and stable visual surround the effect of alcohol was close to significance (p less than 0.069). When the head was tilted to either side, no effect of alcohol was detected, nor in the movement coordination test. It is concluded that dynamic posturography can detect the effect of alcohol on static and dynamic equilibrium. Test conditions with absent vision appear to be the most sensitive. The results in static conditions are well in agreement with previous studies; the findings under dynamic conditions are new.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ledin</LastName><ForeName>T</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of ENT, University Hospital, Linköping, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Odkvist</LastName><ForeName>L M</ForeName><Initials>LM</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Norway</Country><MedlineTA>Acta Otolaryngol Suppl</MedlineTA><NlmUniqueID>0370355</NlmUniqueID><ISSNLinking>0365-5237</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>3K9958V90M</RegistryNumber><NameOfSubstance UI="D000431">Ethanol</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CitationSubset>S</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000428" MajorTopicYN="N">Alcohol Drinking</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000704" MajorTopicYN="N">Analysis of Variance</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000431" MajorTopicYN="N">Ethanol</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009760" MajorTopicYN="N">Nystagmus, Physiologic</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004856" MajorTopicYN="N">Postural Balance</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011187" MajorTopicYN="Y">Posture</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1991</Year><Month>1</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1991</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1991</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">1927474</ArticleId><ArticleId IdType="doi">10.3109/00016489109131475</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Suède</li></country></list><tree><noCountry><name sortKey="Odkvist, L M" sort="Odkvist, L M" uniqKey="Odkvist L" first="L M" last="Odkvist">L M Odkvist</name></noCountry><country name="Suède"><noRegion><name sortKey="Ledin, T" sort="Ledin, T" uniqKey="Ledin T" first="T" last="Ledin">T. 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